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  • Bone Strain in the Patella
    Patellofemoral complications, specifically patellar fracture and anterior knee pain, remain a cause for total knee replacement revision. Subject-specific finite element (FE) models developed from imag
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  • Population Based Implant Evaluations
    The performance of total knee replacement implants is sensitive to intersubject and surgical variability. Subject-specific finite element (FE) analyses have been used to evaluate the joint mechanics o
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  • Mass and Fluid Transport in the Lymphatic System
    The lymphatic system plays a vital role in fluid balance and homeostasis within the body. It is responsible for the transport of lymph from the interstitium to the venous return. The secondary lymphat
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  • Circle of Willis Flow Analysis
    The Circle of Willis (CoW) is located at the base of the brain providing the primary vascular link to the heart. The communicating arteries of the CoW form a bridge between the cerebral arteries and a
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  • CFD following fEVAR
    Fenestrated Endovascular Aneurysm Repair (fEVAR) is one option for treatment of abdominal aortic aneurysms with inadequate neck length for standard EVAR. The Zenith fEVAR device (Cook Medical Inc.) em
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  • Transcranial Direct Current Stimulation (tDCS)
    Transcranial direct current stimulation (tDCS) represents a neuromodulation technique that delivers a weak direct electrical current to the brain, and can be used to treat brain injuries, strokes, and
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  • Modeling Risks in Cerebral Aneurysms
    Unruptured cerebral aneurysms can represent a significant health risk for patients if not properly diagnosed and treated. A study was carried out to determine if significant geometrical differences co
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  • Variability and Accuracy of Spine Segmentation
    This study involved testing the effectiveness of manual segmentation of lumbar vertebrae, taking into account the proximity of articulating surfaces and degenerative joint changes. Simpleware ScanIP w
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  • Electromagnetic Testing of MRI Systems
    The FE models generated by Simpleware have been used to help optimise coil and spinal array designs, and to investigate patient absorption of EM and RF energy. The reliability of the Simpleware models
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  • Vertebral Endplate Morphology and Permeability
    The vertebra-disc interface in the human spine is a preferential path for both metabolites and fluid exchanges. With aging, degeneration and/or tissue calcification such interface experiences alterati
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